Don't get mislead into focusing on whether whether or not error bars overlap.

Rather than just report which comparisons are, or are not, 'statistically significant', Prism can report multiplicity adjusted P values for many tests, and these can be more informative than a simple statement about which comparisons are statistically significant or not.

It is better in many cases to focus on the the size of the difference and the precision of that value quantified as a confidence interval.

“Statistically significant” is not the same as “scientifically important”. Note that the 5% probability is for the family of comparisons, not just for one comparison. If all the data in all groups were really sampled from the same population, then there is a 5% (if you pick the traditional value for alpha) that any one (or more) of the comparisons would be designated as statistically significant. With all the methods except Fisher's LSD, these decisions correct for multiple comparisons.

Owners of earlier versions will need to purchase an upgrade.If you correct for multiple comparisons using statistical hypothesis testing, one of the main results will be a decision for each comparison as to whether it is statistically significant or not. The update is only free to people who already own Prism 7. It is essential that you include your serial number with this request. While running Prism 7.0a/7.0b/7.0c/7.0d, drop the Help menu and choose Check For Updates. If you have any trouble getting the update to work, please email requesting a link to a full installer. Prism Mac 7.0e is also a free update that fixes some bugs.

If you have any trouble getting the update to work, please email requesting a link to a full installer. Please follow these instructions to update from 7.04 to 7.05. Important note for users updating from 7.04: There is a known issue that makes the updating process from 7.04 to 7.05 slightly more complicated. While running Prism 7.00/7.01/7.02/7.03/7.04, drop the Help menu and choose Check For Updates. Prism Windows 7.05 is a free update that fixes several bugs. Please check our Updates page to find the latest version.

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